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Dual Cardiomyopathy in Patients With Coronary Artery Disease

We have dozens of randomized clinical trials that concluded there aren’t tangible prognostic benefits from coronary revascularization in some patients with single or multi-vessel coronary artery disease who are suffering from cardiomyopathy. Such lack of benefit may be explained by non-explored presence of co-incidental non-ischemic cardiomyopathy. Thus, the same patient may have both ischaemic and […]

Branch-ostial lesions: easy but tricky

There is no denying that the main target during PCI are significant proximal lesions in the three main coronary vessels (LAD, RCA and LCX), but sometimes we are faced with ostial significant lesions in sizable side branches that shouldn’t be overlooked (especially, OM and diagonals). We are focusing here on MEDINA 0,0,1 ostial bifurcational affection […]

Drug-eluting balloons: don’t get stuck in small branches

In spite that drug-eluting stents (DES), particularly newer generations,  are the gold standard in treating significant coronary artery lesions, there is at least 2-4% risk of target lesion failure (TLF) per year, in the form of in-stent restenosis (ISR). The risk of In-stent restenosis (ISR) is invariably higher when you are obliged to use smaller […]

Dyspnea of Ticagrelor: the challenge and the wise decisions

Ticagrelor is one of the most potent anti-platelets, especially for acute coronary syndrome patients managed with PCI and stenting. However, Ticagrelor induced dyspnea is one of the most annoying adverse effects that may disrupt patients compliance to this vital medication. Some patients may seek re-admission shortly after PCI complaining from this dyspnea, and it may […]

Statins and dementia: the everlasting debate 

Statins are among the most widely prescribed medications in the realm of cardiology and preventive medicine. It is estimated that more than 200 million people are on statin therapy worldwide, so all issues regarding its safety and possible side effects are of unique importance. The vast majority of statin users are elderly people suffering form […]

AF and frail elderly population: a newer evidence for the hard decision

Stroke or bleeding?. This isn’t a rational choice, however this is the bitter truth in many frail elderly patients in whom therapeutic anti-caogulation is indicated for atrial fibrillation. Frail elderly people represent a uniquely fragile group of AF patients as they are gravely prone to both risks of thrombosis and bleeding. Most frail old patients […]